Every scene, fully restored. Every job, verified.
Bio-One of Fort Myers handles biohazard, crime scene, and trauma cleanup with discretion and certified, compliant protocol — for Lee, Charlotte, Collier, DeSoto, Glades & Hendry counties.

Six counties, no two alike
Southwest Florida isn't one market — it's several, and treating it that way is part of the job. Lee County alone runs from barrier-island beach communities through Fort Myers to inland Lehigh Acres, spanning more property types and law-enforcement jurisdictions than anywhere else we serve, with parts of its coastal construction still recovering from Hurricane Ian. Cape Coral's slab-on-grade housing stock means a biohazard job often means sealing the concrete slab itself, not just replacing flooring. Naples and Bonita Springs bring high-rise and beachfront condo work that runs through HOA and building-management coordination as often as a homeowner directly. DeSoto, Glades, and Hendry counties are rural and agricultural — citrus, cattle, and sugar country — where private septic is the norm and a property's remote location can mean a longer discovery time before anyone calls. Same certified protocol, same crew, every time — but we show up already knowing which county we're walking into.
Need help right now?
For active emergencies, call us directly — we answer 24/7, day or night.
Call (239) 464-2231Or request service online
View full contact page →"I called Bio-One from out of state to clean the house of a family member that passed away alone inside. I was initially concerned with trusting a company to go in the empty house unattended. Michelle was very professional, courteous, and sincere, and made me feel very comfortable with their ability to handle the job. Weeks later I went to the house and it was fine. The room was cleaned up and there were no traces anything happened in the house. Alex did a great job. To speak to their trustworthiness, there was money still sitting on the dresser in the same room that was cleaned. I'd definitely recommend Bio-One. Thank you guys for making a difficult time a little bit easier."
Kenneth Wulle"Bio-One is a truly awesome company. Alex was so very compassionate and understanding. Alex was able to get me scheduled as soon as I was released from the hospital. Alex & Chris arrived as scheduled and worked diligently until the problem/mess was completely cleaned and removed from my home. Heaven forbid anyone should need this service but if you find yourself in a similar predicament you absolutely should hire Bio-One. Highly recommend this company. I was totally satisfied with the job done by Alex and Chris."
Judy Stewart"Michelle and Alex were very kind and helpful throughout a difficult family situation. They are willing to work with you to fit your specific cleaning needs and budget. Without them it would have been extremely difficult and unpleasant to go through mementos and paperwork in our family member's house. I wouldn't hesitate to recommend Bio-One to anyone in need of their services."
Rob Riddle"Michelle was absolutely wonderful to talk to after I found out of my father's passing in his home. I had no clue what I was in for. She was caring and walked me through the process step by step. She set up a time to meet with her husband Alex and explained what should expect. When Alex arrived, he was absolutely wonderful and gave me condolences. He was honest and respectful in every manner. I could have not done this without Alex being honest. Thank you for all you have done and God Bless You!"
Andrea Struwe"We called Bio-One from out of state when my step-father passed. Michelle and Alex were amazingly empathetic and helpful. They worked around our travel schedule and gave us an economical short-term solution to make his home pleasant (and safe) to be in while developing a longer term plan. I highly recommend their services!!"
Sheila Bengtson"Over the last 7 months my family has had to sort out the complicated, multi-layered, and sad situation surrounding my father transitioning into long-term care. Because my sister and I live very far away, we've had to sort things out from a distance. We don't know what we would have done without Alex at Bio-One in Fort Myers. He was so responsive and took care of the cleanout, sanitization and carpet removal. He was so very kind and understanding. I highly recommend Bio-One Fort Myers."
Patrick Sullivan"They seem to deal mostly with more emergency and biohazard situations but they also served our use-case of hoarding very well. Most teams would likely not want to even take the job when they realize just how much stuff there is, especially when food perishables are involved. Alex and team were extremely professional yet flexible. They were also some of the nicest people to interact with just in general."
Terry Liu"Bio-One restored my life. Bio-One treated me with respect, compassion and kindness while working to clean out furniture, garbage and remove pet odor. Bio-One thoroughly went room to room, top to bottom ensuring not area was missed. Which brought peace of mind for me. It was a very emotional few days and now being on the other-side - I am regenerated and smiling again."
Deborah Griffin"I called Bio-One from out of state to clean the house of a family member that passed away alone inside. I was initially concerned with trusting a company to go in the empty house unattended. Michelle was very professional, courteous, and sincere, and made me feel very comfortable with their ability to handle the job. Weeks later I went to the house and it was fine. The room was cleaned up and there were no traces anything happened in the house. Alex did a great job. To speak to their trustworthiness, there was money still sitting on the dresser in the same room that was cleaned. I'd definitely recommend Bio-One. Thank you guys for making a difficult time a little bit easier."
Kenneth Wulle"Bio-One is a truly awesome company. Alex was so very compassionate and understanding. Alex was able to get me scheduled as soon as I was released from the hospital. Alex & Chris arrived as scheduled and worked diligently until the problem/mess was completely cleaned and removed from my home. Heaven forbid anyone should need this service but if you find yourself in a similar predicament you absolutely should hire Bio-One. Highly recommend this company. I was totally satisfied with the job done by Alex and Chris."
Judy Stewart"Michelle and Alex were very kind and helpful throughout a difficult family situation. They are willing to work with you to fit your specific cleaning needs and budget. Without them it would have been extremely difficult and unpleasant to go through mementos and paperwork in our family member's house. I wouldn't hesitate to recommend Bio-One to anyone in need of their services."
Rob Riddle"Michelle was absolutely wonderful to talk to after I found out of my father's passing in his home. I had no clue what I was in for. She was caring and walked me through the process step by step. She set up a time to meet with her husband Alex and explained what should expect. When Alex arrived, he was absolutely wonderful and gave me condolences. He was honest and respectful in every manner. I could have not done this without Alex being honest. Thank you for all you have done and God Bless You!"
Andrea Struwe"We called Bio-One from out of state when my step-father passed. Michelle and Alex were amazingly empathetic and helpful. They worked around our travel schedule and gave us an economical short-term solution to make his home pleasant (and safe) to be in while developing a longer term plan. I highly recommend their services!!"
Sheila Bengtson"Over the last 7 months my family has had to sort out the complicated, multi-layered, and sad situation surrounding my father transitioning into long-term care. Because my sister and I live very far away, we've had to sort things out from a distance. We don't know what we would have done without Alex at Bio-One in Fort Myers. He was so responsive and took care of the cleanout, sanitization and carpet removal. He was so very kind and understanding. I highly recommend Bio-One Fort Myers."
Patrick Sullivan"They seem to deal mostly with more emergency and biohazard situations but they also served our use-case of hoarding very well. Most teams would likely not want to even take the job when they realize just how much stuff there is, especially when food perishables are involved. Alex and team were extremely professional yet flexible. They were also some of the nicest people to interact with just in general."
Terry Liu"Bio-One restored my life. Bio-One treated me with respect, compassion and kindness while working to clean out furniture, garbage and remove pet odor. Bio-One thoroughly went room to room, top to bottom ensuring not area was missed. Which brought peace of mind for me. It was a very emotional few days and now being on the other-side - I am regenerated and smiling again."
Deborah GriffinWe treat every property like it matters — because it's someone's home.
From the first call to the final walkthrough, every step is documented: who responded, what was removed, how it was disposed of, and proof the space is safe to live in again.
Discreet arrival
Unmarked vehicles and plain-clothed technicians — neighbors never know, and no special requests go unmet.
Certified protocol
OSHA-compliant biohazard handling and manifested waste disposal, every time, on every job.
Verified restoration
We don't leave until the property is fully habitable and operational again — documented, photographed, confirmed.
What we handle
24 specialized services across biohazard remediation, crime & trauma scene cleanup, and hoarding response.
Covering Southwest Florida
Based in Fort Myers, dispatching across six counties.
Lee CountyAs our home county, Lee County typically sees the fastest on-site response times of anywhere we serve.
Charlotte CountyWe regularly dispatch to Charlotte County and coordinate closely with local property managers and families.
Collier CountyCollier County jobs are coordinated the same way as our Lee County calls: fast response, unmarked vehicles, full discretion.
DeSoto CountyWe coordinate DeSoto County jobs directly by phone to confirm timing before dispatching a crew.
Glades CountyGlades County calls are scheduled with a confirmed arrival window given the distance from our Fort Myers base.
Hendry CountyWe work with Hendry County families and property managers to schedule service around travel time from Fort Myers.
Restored, not just cleaned
Real jobs, real technicians — not stock photography.
Field response
Client consultation
Site assessment
Before / after
In-depth evaluation
Before / after
Before / after
Credentials you can actually verify
Licensed & Insured
Fully bonded for residential, commercial & industrial jobs.
OSHA-Compliant Protocol
Bloodborne pathogen & biohazard handling standards on every job.
Manifested Waste Disposal
Regulated medical waste tracked from pickup to destruction.
Direct Insurance Billing
We coordinate with your carrier so you don't have to.
Law Enforcement Liaison
Experienced working alongside police, victim advocates & property managers.
24/7/365 Availability
Real people answer, day or night, holidays included.
How it works
Call & assess
Describe the situation — we walk you through what to expect before anyone arrives.
Certified cleanup
Our technicians arrive discreetly and begin documented, compliant remediation.
Verified restoration
We confirm the property is safe and habitable — and handle the paperwork with your insurer.
The people who show up
Family owned and operated — the same team every time, not a rotating crew of strangers.
Alex
"To speak to their trustworthiness — there was money still sitting on the dresser in the same room that was cleaned." — Kenneth W., Google review
Michelle
"Michelle was very professional, courteous, and sincere, and made me feel very comfortable." — Kenneth W., Google review
What Fort Myers says
A selection of 8 reviews from our 11-review Google profile — read every review on Google →
"I called Bio-One from out of state to clean the house of a family member that passed away alone inside. I was initially concerned with trusting a company to go in the empty house unattended. Michelle was very professional, courteous, and sincere, and made me feel very comfortable with their ability to handle the job. Weeks later I went to the house and it was fine. The room was cleaned up and there were no traces anything happened in the house. Alex did a great job. To speak to their trustworthiness, there was money still sitting on the dresser in the same room that was cleaned. I'd definitely recommend Bio-One. Thank you guys for making a difficult time a little bit easier."
"Bio-One is a truly awesome company. Alex was so very compassionate and understanding. Alex was able to get me scheduled as soon as I was released from the hospital. Alex & Chris arrived as scheduled and worked diligently until the problem/mess was completely cleaned and removed from my home. Heaven forbid anyone should need this service but if you find yourself in a similar predicament you absolutely should hire Bio-One. Highly recommend this company. I was totally satisfied with the job done by Alex and Chris."
"Michelle and Alex were very kind and helpful throughout a difficult family situation. They are willing to work with you to fit your specific cleaning needs and budget. Without them it would have been extremely difficult and unpleasant to go through mementos and paperwork in our family member's house. I wouldn't hesitate to recommend Bio-One to anyone in need of their services."
A hard day doesn't have to get harder.
Call now for a discreet, no-obligation assessment — day or night.
Call (239) 464-2231 →